TRANSLATIONAL PHYSIOLOGY Resolvin D1 reverses reactivity and Ca sensitivity induced by ET-1, TNF- , and IL-6 in the human pulmonary artery
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چکیده
Roddy Hiram, Edmond Rizcallah, Chantal Sirois, Marco Sirois, Caroline Morin, Samuel Fortin, and Eric Rousseau Department of Physiology and Biophysics, Université de Sherbrooke, Sherbrooke, Quebec, Canada; Department of Pathology, Université de Sherbrooke, Sherbrooke, Quebec, Canada; Service of Thoracic Surgery Faculty of Medicine and Health Sciences, Université de Sherbrooke, Sherbrooke, Quebec, Canada; and SCF Pharma, Ste-Luce, Quebec, Canada
منابع مشابه
Resolvin D1 reverses reactivity and Ca sensitivity induced by ET-1, TNF- , and IL-6 in the human pulmonary artery
Roddy Hiram, Edmond Rizcallah, Chantal Sirois, Marco Sirois, Caroline Morin, Samuel Fortin, and Eric Rousseau Department of Physiology and Biophysics, Université de Sherbrooke, Sherbrooke, Quebec, Canada; Department of Pathology, Université de Sherbrooke, Sherbrooke, Quebec, Canada; Service of Thoracic Surgery Faculty of Medicine and Health Sciences, Université de Sherbrooke, Sherbrooke, Quebec...
متن کاملResolvin D1 reverses reactivity and Ca2+ sensitivity induced by ET-1, TNF-α, and IL-6 in the human pulmonary artery.
Pulmonary hypertension (PH) is a rare and progressive disease characterized by an inflammatory status and vessel wall remodeling, resulting in increased pulmonary artery resistance. During the last decade, treatments have been proposed; most of them target the endothelial pathways that stimulate smooth muscle cell relaxation. However, PH remains associated with significant morbidity. We hypothe...
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Roddy Hiram, Edmond Rizcallah, Sofia Marouan, Chantal Sirois, Marco Sirois, Caroline Morin, Samuel Fortin, and Eric Rousseau Department of Pharmacology and Physiology, Université de Sherbrooke, Sherbrooke, Quebec, Canada; Department of Obstetrics-Gynecology, Université de Sherbrooke, Sherbrooke, Quebec, Canada; Department of Pathology, Université de Sherbrooke, Sherbrooke, Quebec, Canada; Servi...
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Objective(s): Acute lung injury (ALI) has a high mortality rate and is characterized by damage to pulmonary system giving rise to symptoms such as histological alteration, lung tissue edema and production of proinflammatory cytokine. p-Coumaric acid (p-CA), as a phenolic compound, that is found in many types of fruits and vegetables has been reported to exhibit a thera...
متن کاملResolvin D1 Attenuates Mpp+-Induced Parkinson Disease via Inhibiting Inflammation in PC12 Cells
BACKGROUND We investigated the influence of Resolvin D1 (RvD1) on the inflammatory response in PC12 cells (a cell model of Parkinson disease, PD). MATERIAL AND METHODS 4 mmol/L 1-methyl-4-phenylpyridinium ion (Mpp+) was used in PC12 cells for an in vitro PD model. 3-(4,5-dimethyl-2-thiazolyl)-2, 5-diphenyl-2-H-tetrazolium bromide (MTT) assay was used to explore PC12 cell viability. Western blot...
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تاریخ انتشار 2014